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Open AccessArticle
by Achille Marino SciProfilesScilitPreprints.orgGoogle Scholar Paola Baldassarre SciProfilesScilitPreprints.orgGoogle Scholar Cristina Ferrigno SciProfilesScilitPreprints.orgGoogle Scholar Andrea Biuso SciProfilesScilitPreprints.orgGoogle Scholar Martina Minutoli SciProfilesScilitPreprints.orgGoogle Scholar Francesco Baldo SciProfilesScilitPreprints.orgGoogle Scholar Stefania Costi SciProfilesScilitPreprints.orgGoogle Scholar Maurizio Virgilio Gattinara SciProfilesScilitPreprints.orgGoogle Scholar Roberto Felice Caporali SciProfilesScilitPreprints.orgGoogle Scholar Cecilia Beatrice Chighizola SciProfilesScilitPreprints.orgGoogle ScholarAchille Marino
,
Paola Baldassarre
Cristina Ferrigno
Andrea Biuso
Martina Minutoli
Francesco Baldo
Stefania Costi
Maurizio Virgilio Gattinara
Roberto Felice Caporali
Cecilia Beatrice Chighizola
1
Unit of Pediatric Rheumatology, ASST G. Pini-CTO, 20122 Milan, Italy
2
Department of Biomedical and Clinical Sciences, Buzzi Children’s Hospital, University of Milan, 20122 Milan, Italy
3
Department of Clinical Sciences and Community Health, Research Center for Pediatric and Adult Rheumatic Diseases (RECAP.RD), University of Milan, 20122 Milan, Italy
4
Department of Rheumatology and Medical Sciences, ASST G. Pini-CTO, 20122 Milan, Italy
*
Author to whom correspondence should be addressed.
Children 2024, 11(5), 600; https://doi.org/10.3390/children11050600
Submission received: 12 April 2024/Revised: 9 May 2024/Accepted: 13 May 2024/Published: 16 May 2024
(This article belongs to the Special Issue Rheumatic Diseases in Children: 2nd Edition)
Abstract
The diagnosis of juvenile idiopathic arthritis (JIA) is often entrusted to the pediatric rheumatologist specialist. Timely referral to a specialized center is crucial. This study aims to assess the consultation and investigation patterns of patients with joint complaints before rheumatology referral. This longitudinal cohort study included patients with joint complaints who were referred to the Pediatric Rheumatology Unit. The cohort included 301 patients (58% female), 50 of them (17%) diagnosed with JIA. Compared to patients with orthopedic conditions or functional diseases, JIA patients had seen more specialists (p < 0.01) and received a quicker diagnosis (p < 0.01). Patients with early JIA diagnosis (within 3 months from symptoms onset) were younger (8.46 vs. 11.5 years old; p = 0.04), more frequently female (78% vs. 47%, p = 0.03), and with higher erythrocyte sedimentation rate (ESR) values (37 vs. 9 mm/h; p = 0.02) than those diagnosed later. Patients with a late diagnosis of JIA had a significantly longer median time between the first healthcare visit and the PR referral (25 vs. 101 days; p < 0.01). The main contributor to diagnostic delay in JIA was the time required for PR referral after the first healthcare consult. Younger age, female sex, and higher ESR values were associated with earlier diagnosis of JIA.
Keywords: juvenile idiopathic arthritis; referral; joint complaints
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MDPI and ACS Style
Marino, A.; Baldassarre, P.; Ferrigno, C.; Biuso, A.; Minutoli, M.; Baldo, F.; Costi, S.; Gattinara, M.V.; Caporali, R.F.; Chighizola, C.B.Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis. Children 2024, 11, 600.https://doi.org/10.3390/children11050600
AMA Style
Marino A, Baldassarre P, Ferrigno C, Biuso A, Minutoli M, Baldo F, Costi S, Gattinara MV, Caporali RF, Chighizola CB.Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis. Children. 2024; 11(5):600.https://doi.org/10.3390/children11050600
Chicago/Turabian Style
Marino, Achille, Paola Baldassarre, Cristina Ferrigno, Andrea Biuso, Martina Minutoli, Francesco Baldo, Stefania Costi, Maurizio Virgilio Gattinara, Roberto Felice Caporali, and Cecilia Beatrice Chighizola.2024. "Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis" Children 11, no. 5: 600.https://doi.org/10.3390/children11050600
Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.
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MDPI and ACS Style
Marino, A.; Baldassarre, P.; Ferrigno, C.; Biuso, A.; Minutoli, M.; Baldo, F.; Costi, S.; Gattinara, M.V.; Caporali, R.F.; Chighizola, C.B.Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis. Children 2024, 11, 600.https://doi.org/10.3390/children11050600
AMA Style
Marino A, Baldassarre P, Ferrigno C, Biuso A, Minutoli M, Baldo F, Costi S, Gattinara MV, Caporali RF, Chighizola CB.Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis. Children. 2024; 11(5):600.https://doi.org/10.3390/children11050600
Chicago/Turabian Style
Marino, Achille, Paola Baldassarre, Cristina Ferrigno, Andrea Biuso, Martina Minutoli, Francesco Baldo, Stefania Costi, Maurizio Virgilio Gattinara, Roberto Felice Caporali, and Cecilia Beatrice Chighizola.2024. "Pre-Rheumatology Referral Consultation and Investigation Pattern in Children with Joint Complaints: Focus on Juvenile Idiopathic Arthritis" Children 11, no. 5: 600.https://doi.org/10.3390/children11050600
Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.
Children,EISSN 2227-9067,Published by MDPI
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